|
KMID : 0882420100780060761
|
|
Korean Journal of Medicine
2010 Volume.78 No. 6 p.761 ~ p.765
|
|
|
A case of rapidly progressive renal failure induced by cadmium intoxication
|
|
Lee Eun-Young
Shin Ho-Sik
Jung Yeon-Soon
Chun Bong-Kwon
Rim Hark
|
|
|
Abstract
|
|
|
|
Cadmium (Cd)-induced renal damage primarily affects the cellular and functional integrity of the proximal tubules. Cd intoxication is a rare cause of Fanconi syndrome. We report a 31-year-old woman with Fanconi syndrome confirmed by laboratory findings and a renal biopsy that also showed an elevated urinary Cd. Seven months before admission, the patient had a normal urinalysis and renal function. Six and 3 months before admission, the patient ingested Chinese herbal mixtures. On admission, the blood Cd concentration was normal, and the urine Cd concentration was 58 μg/g of creatinine, 29-times higher than the normal range. A renal biopsy showed degeneration of the proximal tubules with normal glomeruli. The serum creatinine had increased from 1.2 to 3.2 mg/dL over 8 months. This case of Fanconi syndrome and rapidly progressive renal damage over a short period was associated with elevated urinary Cd levels. (Korean J Med 78:761-765, 2010)
|
|
|
KEYWORD
|
|
|
Kidney failure, Fanconi syndrome, Cadmium
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|